
They may bring tears to your eyes, but onions could also be silently saving your life. While garlic often steals the spotlight in the world of natural medicine, the humble onion may be the real unsung hero when it comes to fighting chronic diseases. What if this everyday kitchen staple held powerful secrets capable of slashing your risk of cancer, brain disease, and even stroke? Keep reading—you’ll never look at an onion the same way again.
Key Takeaways
-
Cancer-Fighting Powerhouse: Onions, especially red varieties, are rich in quercetin and anthocyanins, which disrupt cancer cell growth and trigger their self-destruction.
-
Multi-Disease Protection: The antioxidants in onions support the body in fending off obesity, diabetes, stroke, Alzheimer’s, and Parkinson’s.
-
Joint and Heart Health Benefits: Compounds in onions reduce cartilage-damaging enzymes and lower the risk of blood clots and arterial problems.
Surprising Link Between Onions and Longevity
Although onions are members of the Allium family of plants and are close relatives to garlic, they seem to get a lot less attention for their health benefits than their more celebrated botanical cousins.
Nevertheless, onions contain important natural substances for improving health and fighting off chronic disease that should not be overlooked. For example, onions can help you fend off cancer, diabetes, obesity, stroke, Alzheimer’s disease, and Parkinson’s disease.
While you may not think of onions as a cancer fighter, they are. The natural chemicals in onions can help reduce the risk of some of our most common and deadly cancers.
Take colorectal cancers, for instance, which are diagnosed in about 150,000 people a year in the U.S. Statistics show every year, more and more younger people are being diagnosed with this disease – recently there’s been about a one percent annual increase in its incidence in folks under the age of 50.1
A study in Asia compared the diets of more than 800 people with colorectal cancer to folks without the cancer. The researchers found that folks who ate the most onions and other allium vegetables (which include leeks and chives as well as garlic) enjoyed a dramatic reduction in the risk of colorectal cancer-- almost 80 percent.2
That’s an astounding result! But onions’ anti-cancer power has been shown in other studies as well.
Superfood Tumor Fighter
When researchers at the University of Guelph in Canada finished researching how onions can help the body resist the formation of tumors, they started referring to onions as a cancer-fighting “superfood.”
The Canadians focused in particular on red onions. Red onions not only contain a high level of quercetin, a flavonoid in all onions that is a well-known antioxidant and inflammation fighter, but they also are a rich source of anthocyanin, the pigment that gives red onions their scarlet hue.
The team found that the anthocyanin multiplies the antioxidant power of the quercetin.
In their tests, says researcher Abdulmonem Murayyan, "We found onions are excellent at killing cancer cells. They activate pathways that encourage cancer cells to undergo cell death (apoptosis). They promote an unfavorable environment for cancer cells, and they disrupt communication between cancer cells, which inhibits growth."
Along with these effects, a study in Japan demonstrates that a compound in onions called onionin A (ONA) can help to inhibit ovarian cancer and lung cancer.
ONA is the Secret Weapon Against Cancer
In these tests, ONA reduced the growth of ovarian tumors by disrupting the tumor-promoting activities of myeloid cells – blood cells that malignant cells commandeer to spread and metastasize.
And ONA produced similar results with lung cancer cells.
The Japanese researchers believe that ONA can potentially be used to improve the cancer-fighting power of cancer drugs and may turn out to be a useful supplement for use by cancer patients. 4
Onions have also been shown to help:
-
Lower the risk of osteoarthritis: Research in England has indicated that onions and other allium vegetables can interfere with enzymes in joints that produce arthritic damage to cartilage. They contain a compound called diallyl disulfide that helps keep the joints functioning with less pain.5
-
Protect the body against obesity, stroke, diabetes, Alzheimer’s disease, and Parkinson’s disease: Onions contain a moderate amount of EGCG, an antioxidant compound that is also found in green tea. In a review of natural foods like onions that contain EGCG, Italian researchers point out that “EGCG is a strong antioxidant and anti-tumor molecule and has the potential to prevent and counteract several human diseases with chronic metabolic and inflammatory components, such as diabetes, stroke, obesity, Parkinson's, and Alzheimer's diseases.”6
-
Lower the risk of blood clots and heart problems: A review study in England uncovered strong evidence that the natural compounds in onions can prevent problematic blood clots.7 And tests in Japan showed that they support improved arterial function.8
My Takeaway
If you decide to start eating more onions, consuming them in just about any form will get you a serving of natural chemicals that may improve your health. However, deep-fried onions may not be a great idea since they will probably contain damaged fats from the frying oil, which can trigger many of the diseases onions are said to prevent.
If you enjoy raw onions, the folks at Tufts pointed out that uncooked onions contain healthy compounds that are broken down in the cooking process.9 And the researchers at Guelph have evidence that the pigments in red onions offer some extra benefits. But eating any type of onion, as well as other fruits and vegetables, is a good bet for improving your health outlook.
Summary
Often overshadowed by garlic, onions pack a powerful punch against chronic diseases. Rich in antioxidants like quercetin and anthocyanins, red onions in particular have demonstrated potent anti-cancer effects, triggering cell death and blocking tumor communication. The compounds in onions may also support brain health, reduce inflammation, improve joint function, and lower the risk of heart disease and obesity. Whether raw or cooked, onions are proving to be a versatile and underestimated ally in disease prevention.
Frequently Asked Questions
Can onions help fight cancer?
Yes—studies show compounds in onions, like quercetin and anthocyanin, can slow cancer cell growth and promote cancer cell death.
Which type of onion is best for health benefits?
Red onions are especially powerful due to their high levels of anthocyanins and quercetin.
Do cooked onions still offer health benefits?
Yes, though raw onions retain more of their beneficial compounds. Cooking can reduce some antioxidants.
What other diseases can onions help prevent?
Onions may help reduce the risk of Alzheimer’s, Parkinson’s, diabetes, obesity, osteoarthritis, and cardiovascular disease.
How should I eat onions to maximize their benefits?
Raw or lightly cooked onions are ideal. Avoid deep frying, as it can introduce harmful fats.
- American Cancer Society. (n.d.). Key statistics for colorectal cancer.
- Wu, X., Shi, J., & Li, Z. (2019). Allium vegetables are associated with reduced risk of colorectal cancer: A hospital-based matched case-control study in China. Asia-Pacific Journal of Clinical Oncology, 15(5), e132-e141.
- Murayyan, A. I., Manohar, C. M., Hayward, G., & Neethirajan, S. (2017). Antiproliferative activity of Ontario grown onions against colorectal adenocarcinoma cells. Food research international (Ottawa, Ont.), 96, 12–18.
- Fujiwara, Y., Horlad, H., Shiraishi, D., Tsuboki, J., Kudo, R., Ikeda, T., Nohara, T., Takeya, M., & Komohara, Y. (2016). Onionin A, a sulfur-containing compound isolated from onions, impairs tumor development and lung metastasis by inhibiting the protumoral and immunosuppressive functions of myeloid cells. Molecular nutrition & food research, 60(11), 2467–2480.
- Williams, F.M., Skinner, J., Spector, T.D. et al. Dietary garlic and hip osteoarthritis: evidence of a protective effect and putative mechanism of action. BMC Musculoskelet Disord 11, 280 (2010)
- Ghidoli, M., Colombo, F., Sangiorgio, S., Landoni, M., Giupponi, L., Nielsen, E., & Pilu, R. (2021). Food Containing Bioactive Flavonoids and Other Phenolic or Sulfur Phytochemicals With Antiviral Effect: Can We Design a Promising Diet Against COVID-19?. Frontiers in nutrition, 8, 661331
- Griffiths, G., Trueman, L., Crowther, T., Thomas, B., & Smith, B. (2002). Onions--a global benefit to health. Phytotherapy research : PTR, 16(7), 603–615.
- Nakayama, H., Tsuge, N., Sawada, H., & Higashi, Y. (2013). Chronic intake of onion extract containing quercetin improved postprandial endothelial dysfunction in healthy men. Journal of the American College of Nutrition, 32(3), 160–164.
- Tufts Health & Nutrition Letter. (n.d.). Are raw onions more nutritious than cooked onions? Tufts University.