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Ancient Anti-Aging Secret: Cycloastragenol and Cycloastragenol Supplement

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Telomere Activation Complex And Mitochondrial Enhancement Matrix.


Ancient Anti-Aging Secret: Cycloastragenol and Cycloastragenol Supplement about Genesis

Ancient Chinese Medicine Secret: Cycloastragenol and Cycloastragenol Supplement

Looking to defy the aging process and support your immune system naturally? The ancient wisdom of Traditional Chinese Medicine (TCM) offers an intriguing solution: cycloastragenol and cycloastragenol supplements. Derived from the roots of the Astragalus membranaceus plant, this powerful compound has gained attention for its potent anti-aging and immune-boosting properties. Let’s uncover the ancient secrets of cycloastragenol and how you can use this supplement to improve your overall health and longevity.

Key Takeaways

  • Cycloastragenol is a plant extract with potent anti-aging and immune-boosting properties.

  • Supplementation with cycloastragenol can support better telomere health, reduce inflammation, and lower oxidative stress for better health.

  • Cycloastragenol's primary mechanism of action is its ability to activate telomerase, an enzyme that plays a key role in maintaining the length of telomeres, the protective caps at the end of chromosomes.

Understanding Cycloastragenol: Origins and Properties

Cycloastragenol is extracted from the roots of the plant Astragalus membranaceus, also known as astragalus root and Mongolian milkvetch. The astragalus membranaceous plant's medicinal use dates back 1,800 years to 200 AD and early Traditional Chinese Medical texts. Ancient Chinese healers used dried roots of the plant to fight illnesses and promote longevity. While these healers couldn't have known about cycloastragenol, they did know that their medicine, called Huangqi, could preserve good health.

Today, modern medicine has revealed that cycloastragenol is a triterpenoid-- that's a diverse group of natural compounds in plants that provide a natural defense against microbes and other attackers. While dangerous to microbes and plant-eating herbivores, when it comes to people, cycloastragenol is known for its potent anti-inflammatory, anti-viral, and immune-boosting properties. That's one reason it has been an essential part of Traditional Chinese Medicine for centuries.

The primary compound present in the plant Astragalus membranaceus is astragaloside IV, which is rich in amino acids. Astragaloside IV and cycloastragenol share a similar chemical structure. The only difference is two sugar groups. But, when it comes to anti-aging, it's cycloastragenol that holds remarkable potential. Modern day research published in the journal Advances in Pharmacology shows cycloastragenol can:

  • Boost and regulate the immune system

  • Support healthy blood pressure

  • Improve heart health

  • Increase cellular health

  • Promote liver health

  • Aid in wound healing

These wide-ranging effects make cycloastragenol an exciting anti-aging supplement. But with such a diverse range of benefits, how does cycloastragenol work? The studies reveal that cycloastragenol has just as many positive actions in the body as it does benefits. It works by:

Cycloastragenol's primary mechanism of action is its ability to activate telomerase, an enzyme that plays a key role in maintaining the length of telomeres.

The Science Behind Cycloastragenol: Telomerase Activation and Anti-Aging Benefits

Telomeres are protective caps on the ends of chromosomes that safeguard them from deterioration. As cells divide, telomeres naturally shorten, eventually reaching a point where they can no longer protect the chromosome, leading to DNA damage and cellular aging. Telomerase is a ribonucleoprotein complex that lengthens telomeres, potentially delaying the aging process. Cycloastragenol is one of the few known natural telomerase activators so it's no wonder that it's getting a lot of attention for its potential to slow the aging process.

Cycloastragenol’s ability to activate telomerase is thought to be linked to the MAPK and PI3K/Akt signaling pathways. Research has shown that cycloastragenol activates telomerase and lengthens telomeres in a telomerase-dependent manner as documented in cell studies and in clinical studies. This telomerase activation has the potential to maintain telomere length and thus delay cellular aging.

The anti-aging benefits derived from cycloastragenol’s activation of telomerase extend beyond just maintaining telomere length. Research has also shown that cycloastragenol can:

  • Increase antioxidant activity in the body by boosting Nrf-2, a transcription factor that regulates the expression of antioxidant proteins

  • Help protect cells from oxidative stress

  • Help prevent age-related degenerative processes caused by oxidative stress

Comparing cycloastragenol to other telomerase activators, its small molecule size and good bioavailability make it an optimal choice for supplementation, enabling lower doses. The low dose required for efficacy also sets cycloastragenol apart from other compounds, which may require larger doses to achieve the same results.

Of course, it's only the beginning of cycloastragenol's positive impact on the body.

Cycloastragenol's Impact on Immune Function

The immune system is your body’s first line of defense against harmful pathogens, viruses and bacteria. A weak immune system can leave you fighting off every cold virus that comes your way. On the other hand, an overactive immune system can result in chronic inflammation and a host of autoimmune illnesses.

Cycloastragenol has been shown to support strong immune function. One of the ways cycloastragenol supports immune function is by activating telomerase and promoting T lymphocyte proliferation. T lymphocytes, called T-cells for short, are a crucial component of the adaptive immune system. They are responsible for identifying and eliminating infected or abnormal cells. By promoting T-cell proliferation, cycloastragenol may help maintain a healthy and responsive immune system.

Several studies support the immune-boosting effects of cycloastragenol. These experiments have consistently demonstrated the ability of cycloastragenol to support immune function by promoting telomere health and reducing inflammation. As a result, cycloastragenol supplements could be a valuable addition to your immune-supporting regimen.

Cardiovascular Health and Cycloastragenol

Cycolastragenol can also help keep your heart strong and healthy. One of the ways cycloastragenol may support cardiovascular health is through its impact on the FXR signaling pathway. Animal studies show that cycloastragenol reduces lipid accumulation in the liver when accompanied by a high-fat diet. This reduction supports balanced blood sugar, blood fats (triglycerides), and liver enzymes (hepatic bile acids). By improving liver function and lipid metabolism, cycloastragenol can help improve blood flow, support healthier blood vessels and arteries as well as improve the overall health of your cardiovascular system.

Cycloastragenol influences proteasome activity - another factor that may aid your heart health. Proteasomes play a crucial role in maintaining cellular health by breaking down damaged or mis-folded proteins. This enhanced proteasome activity may help protect the heart and blood vessels from oxidative stress and inflammatory damage.

In addition to these direct effects on cardiovascular health, cycloastragenol shows overall potential for promoting healthy aging and immune function, which could indirectly support a healthy heart. By supporting telomere and cellular health, reducing inflammation, and improving immune function, cycloastragenol supplements can help maintain cardiovascular health and overall vitality.

Cycloastragenol Supplements: Types, Dosage, and Safety

Cycloastragenol supplements come in several forms, offering different concentrations of this powerful compound. To fully benefit from your cycloastragenol supplement, you'll want to understand the types of supplements available, recommended dosages, and any safety considerations.

Forms of Supplements

Cycloastragenol supplements are available in multiple forms, including capsules, tablets, and liquid extracts. Capsules and tablets are generally the most convenient and easy-to-administer options. Their formulations are designed for optimal absorption and bioavailability of cycloastragenol in the body.

Recommended Dosage

The suggested dosage for cycloastragenol supplements differs based on individual health concerns and intended benefits. A common recommendation is to take one 100mg capsule per day. Dosage suggestions might also differ based on your age and pre-existing health conditions. Consult with your healthcare professional for personalized advice for your specific needs.

The Advantage of Genesis

Green Valley Naturals developed Genesis with a scientifically backed dosage of cycloastragenol to support healthy telomeres and help you look and feel your very best as you age. Genesis is unique because it contains a Telomerase Activation Complex developed from some of the most widely researched natural telomerase activators available today that are shown in science to help you grow younger at the cellular level. These include:

Cycloastragenol (CAG): The ancient Chinese Medicine staple that supports activation of telomerase, improves lipid metabolism, boosts your immune system and has powerful anti-inflammatory and antioxidant properties.

Telos95: This potent antioxidant blend of organic grapevine and olive leaves is shown in research to help slow shortening of telomeres which can help slow the aging process in healthy cells. A study at Princeton Consumer Research found that taking Telos95 for one year may reduce the biological age of telomeres by more than seven years.

Alpha Lipoic Acid (ALA): An antioxidant made in your cells that helps turn glucose into energy. Scientists at Emory University School of Medicine have found that ALA can stimulate telomerase.

In addition to this foundation, you get the benefits of:

Pterostilbene: Pterostilbene is a polyphenol compound that occurs naturally in plants. It's the main antioxidant in blueberries and is also found in nuts. Pterostilbene can lower harmful inflammation linked to aging as well as support healthy telomere length. Lab research in Italy indicates that pterostilbene can boost longevity in a variety of ways that are still being investigated.

CoQ10: Coenzyme Q10 plays a vital role in helping the mitochondria produce energy for cells. Research at the National Institute on Aging demonstrates that this important antioxidant can alleviate symptoms of aging and improve cellular bioenergetics.

Grape Seed extract: Grape seed extract has twice the antioxidant capacity of red wine extract (resveratrol). This may be because grape seed extract has a higher level of resveratrol. Resveratrol significantly increases telomerase activity. Grape seed extract has also been shown to improve cholesterol markers, reduce blood pressure and fight inflammation, which may lower the risk of heart disease. Lab studies show that grape seed extract can protect against age-related genetic damage to the central nervous system and the brain. It may also help support better function of the immune system as you age.

Vitamin D: Studies also show that getting enough vitamin D may slow the aging of your cellular DNA and work with telomerase to keep telomeres longer. What's more, as you age, keeping your vitamin D levels up may lower your risk of cognition problems, depression, osteoporosis, heart disease, diabetes and cancer. Epidemiological research shows that older folks missing out on Vitamin D are more likely to suffer from these conditions.

Vitamin K2 (menaquinone): A wide range of research demonstrates that Vitamin K2 activates important proteins that protect against age-related health problems. Those proteins keep arteries healthier, support strong bones and promote a strong, sharp memory. Vitamin K2 also improves insulin sensitivity and may lower the risk of cancer.

Summary: Ancient Anti-Aging Secret: Cycloastragenol and Cycloastragenol Supplement

Cycloastragenol, a popular remedy in Traditional Chinese Medicine derived from the plant Astragalus membranaceus, offers unique benefits for improving your health and the way you age. Its ability to activate telomerase, promote cellular health, boost immune health and reduce inflammation make it a promising supplement for overall health and well-being. Cycloastragenol is the foundation of the anti-aging supplement Genesis, making it a valuable addition to your daily health regimen.

As the world of cycloastragenol research continues to unfold, we should discover even more about its potential benefits and applications. Until then, this ancient root has the potential to support your health and vitality moving you forward on your journey towards radiant wellness and longevity.

Frequently Asked Questions

Does Cycloastragenol reverse aging?

Cycloastragenol has been found to reverse outward signs of aging, boost your immune system and heart health, improve your physical endurance and bone density. So yes, it appears to have many positive effects in reversing how your body ages.

What supplement can repair telomeres?

Cycloastragenol has been found to support healthy telomere length by increasing levels of telomerase in the body. In addition, B vitamins such as folate and vitamin B12 have been shown to contribute to telomere repair, with studies proving positive relationships between their use and telomere length. Higher levels of vitamin B12 than what's normally found in the body and achieved through supplementation can reduce inflammation and oxidative stress, potentially explaining the longer telomeres associated with its use.

How much Cycloastragenol is in Astragalus?

Astragalus root extract contains 10 percent cycloastragenol, equating to 20mg per capsule. That's why anti-aging experts recommend supplementing with a cycloastragenol supplement such as Genesis which provides many times that. Genesis offers a Telomerase Activation Complex featuring cycloastragenol and other telomerase activators such as Telos95 at a combined dosage of 265mg.

What is the difference between Cycloastragenol and astragaloside?

Cycloastragenol (CAG) is a bioactive molecule derived from Astragalus species, while Astragaloside IV (AG) is the main compound found in Astragalus membranaceus. CAG is a product of AG and is obtained through the process of AG hydrolysis. Therefore, the difference between Cycloastragenol and Astragaloside is that CAG is derived from a species of Astragalus, while AG is the main component of Astragalus membranaceus.

What is cycloastragenol and where does it come from?

Cycloastragenol is a triterpenoid derived from Astragalus membranaceus, commonly known as astragalus root. This plant has been used in Traditional Chinese Medicine for centuries as an anti-aging remedy.

Yu Y, Zhou L, Yang Y, Liu Y. Cycloastragenol: An exciting novel candidate for age-associated diseases. Exp Ther Med. 2018 Sep;16(3):2175-2182. doi: 10.3892/etm.2018.6501. Epub 2018 Jul 20. PMID: 30186456; PMCID: PMC6122403.

A comprehensive review of cycloastragenol: Biological activity, mechanism of action, and structural modifications. August 2022. Mengting He, Ke Wang a, Haojie Che a, Huifang Wang a, Kan Yang c, Guiming Zhang b, Jingchun Yao b, Jinxin Wang a


Astragalus: The Root at the Heart of Anti-Aging

Zhang J, Wu C, Gao L, Du G, Qin X. Astragaloside IV derived from Astragalus membranaceus: A research review on the pharmacological effects. Adv Pharmacol. 2020;87:89-112. doi: 10.1016/bs.apha.2019.08.002. Epub 2019 Dec 18. PMID: 32089240.

Li CX, Liu Y, Zhang YZ, Li JC, Lai J. Astragalus polysaccharide: a review of its immunomodulatory effect. Arch Pharm Res. 2022 Jun;45(6):367-389. doi: 10.1007/s12272-022-01393-3. Epub 2022 Jun 17. PMID: 35713852.

Yu Y, Zhou L, Yang Y, Liu Y. Cycloastragenol: An exciting novel candidate for age-associated diseases. Exp Ther Med. 2018 Sep;16(3):2175-2182. doi: 10.3892/etm.2018.6501. Epub 2018 Jul 20. PMID: 30186456; PMCID: PMC6122403.



Telomere Activation Complex And Mitochondrial Enhancement Matrix.


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